100000 - Document - Document and Entity Information
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100010 - Statement - BALANCE SHEETS
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100020 - Disclosure - Fair Value Measurements - Summary of Investments in an Unrealized Loss Position (Details) 2
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100030 - Disclosure - Leases - Future Minimum Annual Lease Commitments under Non-cancelable Operating Leases (Detail) 2
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100040 - Disclosure - Term Loan - Schedule of Future Principal Payments (Details) 2
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100050 - Statement - BALANCE SHEETS (Parenthetical)
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100060 - Statement - STATEMENTS OF CASH FLOWS 2
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100070 - Statement - STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
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100080 - Statement - STATEMENTS OF STOCKHOLDERS' EQUITY
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100090 - Statement - STATEMENTS OF STOCKHOLDERS' EQUITY (Parenthetical)
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100100 - Statement - STATEMENTS OF CASH FLOWS
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100110 - Statement - STATEMENTS OF CASH FLOWS (Parenthetical)
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100120 - Disclosure - Organization and Principal Activities
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100130 - Disclosure - Summary of Significant Accounting Policies
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100140 - Disclosure - Fair Value Measurements
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100150 - Disclosure - Balance Sheet Components
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100160 - Disclosure - Leases
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100170 - Disclosure - Term Loan
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100180 - Disclosure - Commitments and Contingencies
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100190 - Disclosure - License Agreements
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100200 - Disclosure - Capital Structure
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100210 - Disclosure - Stock-Based Compensation
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100220 - Disclosure - Income Taxes
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100230 - Disclosure - 401(k) Retirement Savings Plan
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100240 - Disclosure - Net Loss Per Share
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100250 - Disclosure - Subsequent Events
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100260 - Disclosure - Summary of Significant Accounting Policies (Policies)
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100270 - Disclosure - Summary of Significant Accounting Policies (Tables)
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100280 - Disclosure - Fair Value Measurements (Tables)
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100290 - Disclosure - Balance Sheet Components (Tables)
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100300 - Disclosure - Leases (Tables)
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100310 - Disclosure - Term Loan (Tables)
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100320 - Disclosure - Capital Structure (Tables)
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100330 - Disclosure - Stock-Based Compensation (Tables)
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100340 - Disclosure - Income Taxes (Tables)
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100350 - Disclosure - Net Loss Per Share (Tables)
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100360 - Disclosure - Organization and Principal Activities - Additional Information (Details)
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100370 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Details)
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100380 - Disclosure - Summary of Significant Accounting Policies - Schedule of Useful Lives of Property and Equipment (Details)
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100390 - Disclosure - Fair Value Measurements - Summary of Financial Assets Measured at Fair Value on Recurring Basis (Details)
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100400 - Disclosure - Fair Value Measurements - Additional Information (Details)
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100410 - Disclosure - Fair Value Measurements - Summary of Investments in an Unrealized Loss Position (Details)
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100420 - Disclosure - Balance Sheet Components - Schedule of Accrued Expenses and Other Current Liabilities (Details)
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100430 - Disclosure - Leases - Additional Information (Details)
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100440 - Disclosure - Leases - Other information related to operating leases (Details)
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100450 - Disclosure - Leases - Future Minimum Annual Lease Commitments under Non-cancelable Operating Leases (Detail)
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100460 - Disclosure - Term Loan - Additional Information (Details)
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100470 - Disclosure - Term Loan - Schedule of Future Principal Payments (Details)
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100480 - Disclosure - License Agreements - Additional Information (Details)
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100490 - Disclosure - Capital Structure - Additional Information (Details)
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100500 - Disclosure - Capital Structure - Summary of Common Stock Reserved for Future Issuance (Details)
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100510 - Disclosure - Stock-Based Compensation - Additional Information (Details)
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100520 - Disclosure - Stock-Based Compensation - Summary of Stock Option Activity - 2020 Equity Incentive Plan (Details)
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100530 - Disclosure - Stock-Based Compensation - Summary of RSU Activity (Details)
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100540 - Disclosure - Stock-Based Compensation - Schedule of Weighted-Average Assumptions to Estimate Fair Value of Stock Options and Purchase Rights Under ESPP Using the Black-Scholes Option-Pricing Model (Details)
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100550 - Disclosure - Stock-Based Compensation - Summary of Stock-Based Compensation Expense Related to Stock Options, RSUs and ESPP (Details)
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100560 - Disclosure - Income Taxes - Additional Information (Details)
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100570 - Disclosure - Income Taxes - Schedule of Reconciliation of the Federal Statutory Income Tax Rate to Effective Tax Rate (Details)
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100580 - Disclosure - Income Taxes - Schedule of Significant Components of Net Deferred Tax Assets and Liabilities (Details)
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100590 - Disclosure - Income Taxes - Schedule of Reconciliation of Beginning and Ending Balance of Unrecognized Tax Benefits (Details)
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100600 - Disclosure - 401(k) Retirement Savings Plan - Additional Information (Details)
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100610 - Disclosure - Net Loss Per Share - Schedule of Computation of Basic and Diluted Net Loss Per Share (Details)
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100620 - Disclosure - Net Loss Per Share - Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Per Share (Details)
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100630 - Disclosure - Subsequent Events - Additional Information (Details)
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Auditor Firm ID
2024
Lessee, Operating Lease, Liability, to be Paid, Year One
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Document Transition Report
Document Transition Report
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Weighted-Average Remaining Contractual Life (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Defined Benefit Plan Disclosure [Line Items]
Defined Benefit Plan Disclosure [Line Items]
Net Cash Provided by (Used in) Operating Activities, Continuing Operations, Total
Cash in operations
Net Cash Provided by (Used in) Operating Activities, Continuing Operations
Payment of offering costs
Payments of Stock Issuance Costs
Number of termination of study and reduction of workforce in percentage
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Geographical [Axis]
Shelf Registration and Sales Agreement.
Shelf Registration and Sales Agreement [Member]
Shelf Registration And Sales Agreement
Vesting period
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Fair Value
Available for sale, fair value
Available for sale securities debt securities
Debt Securities, Available-for-Sale
Other Liabilities, Noncurrent, Total
Other liabilities
Other Liabilities, Noncurrent
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
RSU
RSU
Restricted Stock Units (RSUs) [Member]
Level 1
Fair Value, Inputs, Level 1 [Member]
Entity Public Float
Entity Public Float
Short Term Investments
Short-Term Debt [Member]
2027
Lessee, Operating Lease, Liability, to be Paid, Year Four
Eli Lilly and Company
Eli Lilly And Company [Member]
Eli Lilly and company.
Fair Value Measurements
Fair Value Disclosures [Text Block]
Income Taxes
Income Tax, Policy [Policy Text Block]
Property and equipment, useful Lives
Property, Plant and Equipment, Useful Life
Total accrued expenses and other current liabilities
Accrued expenses and other current liabilities
Accrued expenses and other current liabilities.
Accrued Expenses and Other Current Liabilities
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Unrecognized stock-based compensation expense
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Increase in net valuation allowance
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Non-cash lease expense
Non Cash Lease Expense
Amount of amortization expense for right-of-use asset from leases.
Accrued Research and Development Expenses
Accrued Research And Development Expenses Policy [Text Block]
Accrued research and development expenses.
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Long Term Investments
Long-Term Debt [Member]
Gain (Loss) on Termination of Lease
Gain on lease termination
Gain on termination of lease
Number of shares issuable upon exercise of warrants.
Number Of Shares Issuable Upon Exercise Of Warrants
Number of shares issuable upon the exercise of warrant
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Fair value, less than twelve months
Title of Individual [Domain]
Issuance of common stock and warrants, net of offering costs
Stock Issued During Period Value Of Common Stock And Warrants
Value of common stock and warrants issued.
Percentage of outstanding shares subject to automatic increase in common stock
Percentage Of Outstanding Shares Subject To Automatic Increase In Common Stock
Percentage of outstanding shares subject to automatic increase in common stock.
Subsequent Events
Subsequent Events [Text Block]
Percentage of tax positions likely of being realized upon ultimate settlement
Threshold Percentage Of Tax Positions Likely Of Being Realized Upon Ultimate Settlement
Threshold percentage of tax positions likely of being realized upon ultimate settlement.
Research and Development [Abstract]
Lease liabilities, net of current portion
Operating Lease, Liability, Noncurrent
Operating lease liability, net of current portion
Schedule Of Stock By Class [Table]
Schedule of Stock by Class [Table]
Investments
Investments, Fair Value Disclosure
Investments, Fair Value Disclosure, Total
2016 Equity Incentive Plan
Two Thousand And Sixteen Equity Incentive Plan [Member]
Two thousand and sixteen equity incentive plan.
Number of shares early exercised under any plan
Share Based Compensation Arrangement By Share Based Payment Award Options Early Exercised Shares
Share-based compensation arrangement by share-based payment award, options, early exercised, shares.
Liabilities fair value
Liabilities, Fair Value Disclosure
Liabilities, Fair Value Disclosure, Total
Class Of Stock [Line Items]
Class of Stock [Line Items]
Total current assets
Assets, Current
Vesting
Vesting [Domain]
Liabilities and Equity
Total liabilities and stockholders' equity
Entity Address, State or Province
Entity Address, State or Province
Other
Deferred Tax Assets, Other
Organization And Principal Activities [Table]
Organization And Principal Activities [Table]
Organization and principal activities.
Beginning Balance, Outstanding Stock Options
Ending Balance, Outstanding Stock Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Estimated fair value of warrant.
Estimated Fair Value Of Warrant
Estimated fair value of the warrant
Weighted-average fair value of options granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Total comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Trading Symbol
Trading Symbol
Deferred Tax Assets, Net of Valuation Allowance
Total deferred tax assets
Common Stock, Shares, Issued, Total
Common Stock, Shares, Issued
Common stock, shares sold and issued
Stock-based compensation
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Share-Based Payment Arrangement, Percent
2025
Long-Term Debt, Maturity, Year Two
Fair value of RSUs vested in period
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Fair Value
Numerator:
Net Income (Loss) Attributable to Parent [Abstract]
Short-Term Debt, Commercial Paper Member.
Short-Term Debt, Commercial Paper [Member]
Short Term Debt Commercial Paper Member
Debt Instrument [Table]
Schedule of Long-Term Debt Instruments [Table]
2026
Lessee, Operating Lease, Liability, to be Paid, Year Three
Shares reserved for future issuance
Common Stock, Capital Shares Reserved for Future Issuance
Accumulated Other Comprehensive Loss
AOCI Attributable to Parent [Member]
Long-term Debt, Current Maturities, Total
Term loan, current portion
Long-Term Debt, Current Maturities
Less: term loan, current portion
Probable of achievement member.
Probable Of Achievement [Member]
Probable of Achievement
Entity Address, City or Town
Entity Address, City or Town
Recent Accounting Pronouncements - Not Yet Adopted
Recent Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Recent accounting pronouncements not yet adopted.
Operating Lease, Weighted Average Discount Rate, Percent
Weighted average discount rate
Series B Redeemable Convertible Preferred Stock
Series B Redeemable Convertible Preferred Stock [Member]
Series B redeemable convertible preferred stock.
Operating leases, renew lease term
Lessee, Operating Lease, Renewal Term
Term Loan
Debt Disclosure [Text Block]
Vested and exercisable, Outstanding Stock Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Subsequent Event
Subsequent Event [Member]
Subsequent Event Type
Subsequent Event Type [Axis]
Monthly Anniversary
Share-Based Payment Arrangement, Tranche Two [Member]
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Income tax disclosure table.
Increases based on tax positions related to prior period
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Additional Paid-In Capital
Additional Paid-in Capital [Member]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Property, Plant, and Equipment, Useful Life, Term, Description [Extensible Enumeration]
Current liabilities:
Liabilities, Current [Abstract]
Number of monthly installments
Number of monthly installments.
Number Of Monthly Installments
Debt securities, available-for-sale, Continuous unrealized loss position, 12 months or longer
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Fair value, twelve months or greater
Current assets:
Assets, Current [Abstract]
Counterparty Name
Counterparty Name [Axis]
Preferred Stock, Par Value
Preferred Stock, Par or Stated Value Per Share
Statement of Stockholders' Equity [Abstract]
Vested and expected to vest, Weighted-Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Lease liabilities, current portion
Operating Lease, Liability, Current
Operating lease liability, current portion
Operating Lease, Liability, Current, Total
Debt instrument, maturity date
Debt Instrument, Maturity Date
Aggregate principal amount
Outstanding term loan, after unamortized discount and debt issuance costs
Long-Term Debt
Total
Equity incentive plan, maximum term
Share Based Compensation Arrangement By Share Based Payment Award Maximum Term
Share based compensation arrangement by share based payment award maximum term.
Class of Stock
Class of Stock [Domain]
Cash charges
Restructuring Charges
Restructuring Charges, Total
Loss on disposal of property and equipment
Loss on Disposal of Property and Equipment
Loss on disposal of property and equipment
Vested and expected to vest, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Federal statutory income tax rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Risks and Uncertainties
Risks And Uncertainties Policy [Text Block]
Risks and uncertainties..
Entity Central Index Key
Entity Central Index Key
Number of warrants issued
Class of Warrant or Right, Number of Securities Called by Warrants or Rights
Plan Name
Plan Name [Domain]
Restricted Cash, Noncurrent
Restricted cash, long-term (included in other assets)
Increase (Decrease) in Other Operating Assets, Total
Other assets
Increase (Decrease) in Other Operating Assets
Operating Leases, option to renew lease term description
Lessee, Operating Lease, Option to Extend
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Shares, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures
Money Market Fund Member.
Money Market Fund [Member]
Money Market Fund Member
Total current liabilities
Liabilities, Current
Entity Tax Identification Number
Entity Tax Identification Number
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Lessor, Operating Lease, Renewal Term
Expected lease term
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Proceeds from issuance of term loan, issuance costs
Payments of Debt Issuance Costs
Financial Instruments [Domain]
Denominator:
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Issuance of common stock related to employee stock purchase plan
Stock Issued During Period, Value, Employee Stock Purchase Plan
Total interest under term loan.
Debt Interest
Less: interest
Award Type
Award Type [Axis]
Leases
Lessee, Operating Leases [Text Block]
Tax credit carryforward expiration year
Tax Credit Carryforward Expiration Year
Tax credit carryforward expiration year.
Plan Name
Plan Name [Axis]
Geographical [Domain]
Total assets
Assets
Clinical development milestones member.
Clinical Development Milestones [Member]
Clinical Development Milestones
Retirement Plan Name
Retirement Plan Name [Domain]
Entity Registrant Name
Entity Registrant Name
Executive Officers
Executive Officer [Member]
Lessee, Lease, Description [Line Items]
Retained Earnings (Accumulated Deficit), Ending Balance
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Gross unrealized losses, less than twelve months
Proceeds from issuance of common stock related to employee stock purchase plan
Proceeds from Stock Plans
Total gross proceeds
Accumulated Deficit
Retained Earnings [Member]
Class of Stock
Class of Stock [Axis]
ESPP issued
Issuance of common stock related to employee stock purchase plan,shares
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Minimum
Minimum [Member]
Options termination term, if option holders service terminate
Share Based Compensation Arrangement By Share Based Payment Award Options Termination Term If Option Holders Service Terminate
Share based compensation arrangement by share based payment award options termination term if option holders service terminate.
Collaboration revenue
Revenues
Revenues, Total
Proceeds from exercise of common stock options
Proceeds from Stock Options Exercised
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Shares, Unvested, Ending Balance
Shares, Unvested, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Lease liability
Operating Lease, Liability
Total operating lease liability
Term of automatically increase in common stock available for issuance
Share Based Compensation Arrangement By Share Based Payment Award Term Of Automatically Increase In Common Stock Available For Issuance
Share-based compensation arrangement by share-based payment award, term of automatically increase in common stock available for issuance.
First Anniversary
Share-Based Payment Arrangement, Tranche One [Member]
Revenue Recognition
Revenue [Policy Text Block]
Equity Component
Equity Component [Domain]
Stock Options, Issued and Outstanding
Stock Option
Employee Stock Option [Member]
Computer Software
Software Development [Member]
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Adjustments to reconcile net loss to net cash used in operating activities:
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
First Tranche Term Loan
First Tranche Term Loan [Member]
First tranche term loan.
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net, Total
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net
Less: unamortized debt issuance costs
Measurement Frequency
Measurement Frequency [Axis]
Debt Disclosure [Abstract]
Entity Current Reporting Status
Entity Current Reporting Status
Common stock shares authorized
Common stock, shares authorized
Common Stock, Shares Authorized
Research and Development Expense, Total
Research and development
Research and development expense
Research and Development Expense
Total deferred tax liabilities
Total deferred tax liabilities
Total deferred tax liabilities
Deferred Tax Liabilities, Gross
Daly City, California.
Daly City, California [Member]
Daly City, California
ASSETS
Assets [Abstract]
Net proceeds of common stock
Proceeds from Issuance of Common Stock
Shares remained available for issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Common stock, $0.0001 par value; 200,000,000 shares authorized as of December 31, 2023 and 2022; 41,029,832 and 23,601,004 shares issued and outstanding as of December 31, 2023 and 2022, respectively
Common Stock, Value, Issued, Ending Balance
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Total
Common Stock, Value, Issued
Change in valuation allowance
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Repayment of term loan
Repayment of term loan
Repayments of Long-Term Debt
Repayments of Long-term Debt, Total
Vested and exercisable, Weighted-Average Remaining Contractual Life (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term
Registration Payment Arrangement by Arrangement [Axis]
Maximum amount of sale cCovered in shelf registration statement.
Maximum Amount Of Sale Covered In Shelf Registration Statement
Maximum amount of sale covered in shelf registration statement
Furniture and Fixtures
Furniture and Fixtures [Member]
Current Fiscal Year End Date
Current Fiscal Year End Date
Share-based Payment Arrangement, Noncash Expense, Total
Stock-based compensation expense
Share-Based Payment Arrangement, Noncash Expense
Auditor Name
Loss from operations
Loss from operations
Operating Income (Loss)
Deferred Tax Liabilities Right-of-use Assets
Deferred tax liabilities right-of-use assets.
Operating lease right-of-use asset
Debt securities, available-for-sale, realized gain (loss)
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Debt Securities, Available-for-sale, Realized Gain (Loss), Total
Entity Ex Transition Period
Entity Ex Transition Period
Income Tax Expense (Benefit), Total
Income tax expense
Income Tax Expense (Benefit)
Debt issuance costs
Debt Issuance Costs, Gross
Research and Development
Research and Development Expense [Member]
Decreases based on tax positions related to prior period
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Kaken Pharmaceutical Agreement
Kaken License Agreement [Member]
Kaken License Agreement
Accrued general and administrative expenses
Accrued General And Administrative Expenses
Accrued general and administrative expenses.
Leases
Lessee, Leases [Policy Text Block]
Compensation expense
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Payment, Tax Withholding, Share-Based Payment Arrangement
Tax withholding payments on restricted stock units
Vesting percentage
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Fair market value exercise price percentage
Fair Market Value Exercise Price Percentage
Fair market value exercise price percentage.
Other comprehensive gain (loss), net of tax:
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract]
Reconciliation of cash, cash equivalents, and restricted cash
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Net Loss per Share
Earnings Per Share, Policy [Policy Text Block]
Second Tranche Term Loan
Second Tranche Term Loan [Member]
Second tranche term loan.
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Increases based on tax positions related to current period
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Offering price
Sale of Stock, Price Per Share
Operating expenses:
Operating Expenses [Abstract]
Depreciation, Depletion and Amortization, Nonproduction, Total
Depreciation, Depletion and Amortization, Nonproduction
Depreciation and amortization
Entity Voluntary Filers
Entity Voluntary Filers
Subsequent Events [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Other Assets, Noncurrent, Total
Other assets
Other Assets, Noncurrent
Potential additional payment
Potential Additional Payment
Potential milestone payments payable.
Options granted to purchase shares of common stock
Granted, Outstanding Stock Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Offering costs
Common Stock and Warrant Net Offering Costs
Common stock and warrant net offering costs.
Capital Structure
Equity [Text Block]
Incentive stock options granted description
Incentive Stock Options Granted Description
Incentive stock options granted description.
Cash paid for interest on term loan
Interest Paid, Excluding Capitalized Interest, Operating Activities
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Gross Unrealized Gains
Vested and exercisable, Weighted-Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Stockholders' equity:
Equity, Attributable to Parent [Abstract]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Lease, Cost [Table Text Block]
Other Information Related to Operating Leases
Shares Subject To Outstanding Common Stock Options [Member]
Shares Subject To Outstanding Common Stock Options [Member]
Shares subject to outstanding common stock options.
Entity [Domain]
Entity
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Options vested in period, fair value
Net operating loss carryforwards expiration year
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year.
Earnings Per Share [Abstract]
Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block]
Future Minimum Annual Lease Commitments Under Non-cancelable Operating Leases
Upfront payments
Upfront Payments
Upfront payments
Dividends, Common Stock, Total
Common stock dividends declared
Dividends, Common Stock
Accounting Policies [Abstract]
Common Stock warrants, issued and outstanding
Common Stock Warrants [Member]
Common Stock Warrants [Member]
Concentration of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Earnings Per Share, Basic, Total
Earnings Per Share, Basic
Net loss per share, basic
Commitments and Contingencies
Commitments and contingencies (Note 7)
Stock Options Granted to Nonemployees
Share-Based Payment Arrangement, Nonemployee [Member]
Income Statement [Abstract]
Amount of debt available under the first tranche.
Debt Available First Tranche
Amount of debt available under the first tranche
Operating Lease, Cost
Operating lease costs
Shares available for future issuance under 2020 Equity Incentive Plan
Shares Available For Future Issuance Under Two Thousand And Twenty Equity Incentive Plan [Member]
Shares available for future issuance under two thousand and twenty equity incentive plan.
Retirement Benefits [Abstract]
Vested and expected to vest, Outstanding Stock Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Total stock options outstanding
Statistical Measurement
Statistical Measurement [Domain]
Net cash used in operating activities
Net Cash Provided by (Used in) Operating Activities
Award Type
All Award Types
Document Period End Date
Document Period End Date
Statistical Measurement
Statistical Measurement [Axis]
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Operating Lease, Payments
Cash paid for operating lease liabilities
Earnings Per Share, Diluted, Total
Earnings Per Share, Diluted
Net loss per share,diluted
Balance Sheet Components Disclosure [Abstract]
Balance Sheet Components Disclosure
Deferred Tax Assets, Operating Loss Carryforwards, Total
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Unrecognized tax benefits
Balance at the beginning of the year
Balance at the end of the year
Unrecognized Tax Benefits
Shares Subject to Outstanding Standard Warrants [Member]
Shares Subject to Outstanding Standard Warrants [Member]
Shares subject to outstanding Standard Warrants.
Debt Instrument, Name
Debt Instrument, Name [Domain]
Fair Value Hierarchy and NAV [Domain]
Fair Value Recurring
Fair Value, Recurring [Member]
Operatingleaseterminationmonthandyear
Operating Lease Termination Month And Year
Operating lease termination date
Additional Paid in Capital, Common Stock, Ending Balance
Additional Paid in Capital, Common Stock, Beginning Balance
Additional paid-in capital
Additional Paid in Capital, Common Stock
Net increase (decrease) in cash, cash equivalents, and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect
Schedule of Future Principal Payments
Schedule of Maturities of Long-Term Debt [Table Text Block]
Deferred tax assets operating lease liability.
Deferred Tax Assets Operating Lease Liability
Operating lease liability
Cash, Cash Equivalents, and Short-Term Investments, Total
Cash, Cash Equivalents, and Short-Term Investments
Cash, cash equivalents, and short-term investments
Exercised, Outstanding Stock Options
Number of options exercised
Exercise of common stock options, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
LIABILITIES AND STOCKHOLDERS' EQUITY
Liabilities and Equity [Abstract]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Entity Interactive Data Current
Entity Interactive Data Current
Private Placement
Private Placement [Member]
Deferred offering costs included in accrued expenses
Deferred Offering Costs Included In Accrued Expenses
Deferred offering costs included in accrued expenses.
Grantee Status
Grantee Status [Domain]
Overallotment Option
Over-Allotment Option [Member]
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Summary of investments in an unrealized loss position
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Summary of significant accounting policies.
Equity [Abstract]
Less: present value discount
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Emerging Growth Company Status
Emerging Growth Company Policy Policy [Text Block]
Emerging growth company policy.
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Allowance for credit losses
Debt Securities, Available-for-Sale, Allowance for Credit Loss
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Ending Balance
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Beginning Balance
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Total
Exercised, Weighted-Average Exercise Price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Cash and Cash Equivalents
Cash and Cash Equivalents, Policy [Policy Text Block]
Equity Components
Equity Components [Axis]
Schedule of Reconciliation of Beginning and Ending Balance of Unrecognized Tax Benefits
Summary of Income Tax Contingencies [Table Text Block]
Registration Payment Arrangement, Maximum Potential Consideration
Maximum amount of offering issuance and sale covered in sales agreement
Other liabilities
Increase (Decrease) in Other Operating Liabilities
Increase (Decrease) in Other Operating Liabilities, Total
401(k) Retirement Savings Plan
Retirement Benefits [Text Block]
Proceeds from Sale, Maturity and Collection of Investments, Total
Proceeds from Sale, Maturity and Collection of Investments
Proceeds from maturities of investments
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value Per Share, Vested
Debt instrument prepayment fee percentage.
Debt Instrument Prepayment Fee Percentage
Debt instrument prepayment fee percentage
Local Phone Number
Local Phone Number
Property, Plant and Equipment [Line Items]
Sale of Stock
Sale of Stock [Axis]
End of term payment, percentage.
End Of Term Payment Percentage
End of term payment, percentage
Debt Instrument Interest Rate Percentage Scenario One
Debt Instrument Interest Rate Percentage Scenario One
Floating interest scenario one
Deferred Revenue
Increase (Decrease) in Deferred Revenue
Lease liabilities, current portion
Lease Liability Current
Present value of lessee's discounted obligation for lease payments from leases, classified as current.
Research Tax Credit Carryforward [Member]
Research and Development Tax Credit Carry Forwards
Debt Instrument Interest Rate Percentage Scenario Two
Debt Instrument Interest Rate Percentage Scenario Two
Floating interest scenario two
Restricted Cash, Current
Restricted cash, short-term (included in other current assets)
2020 Employee Stock Purchase Plan
Two Thousand And Twenty Employee Stock Purchase Plan [Member]
Two thousand and twenty employee stock purchase plan.
Stock Option Granted to Executive Officers
Share-Based Payment Arrangement, Employee [Member]
Statement of Cash Flows [Abstract]
Accrued research and development expenses
Accrued Research And Development Expenses
Accrued research and development expenses.
2020 Equity Incentive Plan
Two Thousand And Twenty Equity Incentive Plan [Member]
Two thousand and twenty equity incentive plan.
Income Tax Authority
Income Tax Authority [Domain]
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Summary of significant accounting policies.
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Property and Equipment, Net
Property, Plant and Equipment, Policy [Policy Text Block]
Document Annual Report
Document Annual Report
Short-Term Debt , Corporate Bond Securities Member.
Short-Term Debt , Corporate Bond Securities [Member]
Short Term Debt Corporate Bond Securities Member
Long-Term Debt, US Treasury Securities Member.
Long-Term Debt, US Treasury Securities [Member]
Long Term Debt Us Treasury Securities Member
Common stock par value
Common stock, par value
Common Stock, Par or Stated Value Per Share
Debt Instrument, Interest Rate, Stated Percentage
Interest rate of term loan
Unrecognized stock-based compensation expense expected to be recognized over weighted-average vesting term
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Long-Lived Tangible Asset [Axis]
Vested and expected to vest, Weighted-Average Remaining Contractual Life (Years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
License Agreements
Collaborative Arrangement Disclosure [Text Block]
Maximum
Maximum [Member]
Retirement Plan Name
Retirement Plan Name [Axis]
Proceeds from issuance of private placement
Proceeds from Issuance of Private Placement
Income Tax Examination, Penalties and Interest Expense, Total
Income tax penalties or interest
Income Tax Examination, Penalties and Interest Expense
Operating lease commencement date
Operating Lease Commencement Month And Year
Operating lease commencement date.
South San Francisco, California.
South San Francisco, California [Member]
South San Francisco, California
Organization and Principal Activities
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Level 3
Fair Value, Inputs, Level 3 [Member]
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Deferred tax assets:
Deferred Tax Assets, Gross [Abstract]
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock [Member]
Series A redeemable convertible preferred stock.
Shares Subject to Outstanding Restricted Stock Units [Member]
Shares subject to outstanding restricted stock units.
Shares subject to outstanding RSUs
General and Administrative
General and Administrative Expense [Member]
Issuance of common stock and warrants, net of offering costs, shares
Stock Issued During Period Shares Of Common Stock And Warrants
Number of shares Issued for common stock and warrants.
Forfeited, Outstanding Stock Options
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Document Financial Statement Error Correction [Flag]
Document Financial Statement Error Correction [Flag]
Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
City Area Code
City Area Code
Cash flows from operating activities
Net Cash Provided by (Used in) Operating Activities [Abstract]
Operating Leases, Future Minimum Payments Due
Total minimum rental payments
Intrinsic value of RSUs outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Aggregate Intrinsic Value, Outstanding
Letter of credit issued.
Letter of Credit Issued
letter of credit issued
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Income tax disclosure line items.
Common stockholders voting rights
Common Stock, Voting Rights
General and Administrative Expense, Total
General and administrative
General and Administrative Expense
Grantee Status
Grantee Status [Axis]
Debt Securities, Available-for-Sale, Realized Gain (Loss), Excluding Other-than-temporary Impairment
Debt securities, available-for-sale, realized gain (loss), excluding other-than-temporary impairment
Weighted Average Number of Shares Outstanding, Basic, Total
Weighted Average Number of Shares Outstanding, Basic
Weighted-average shares of common stock outstanding, basic
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Schedule of Weighted-Average Assumptions to Estimate Fair Value of Stock Options and Purchase Rights Under ESPP Using the Black-Scholes Option-Pricing Model
Schedule of Useful Lives of Property and Equipment
Schedule of Property and Equipment Useful Lives [Table Text Block]
Schedule of property and equipment useful lives.
Shares available for future issuance under 2020 Employee Stock Purchase Plan
Employee Stock [Member]
Cash flows from financing activities
Net Cash Provided by (Used in) Financing Activities [Abstract]
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Restricted and performance stock units, issued and outstanding
Restricted and Performance Stock Units, Issued and Outstanding [Member]
Restricted and performance stock units, issued and outstanding.
Statement [Table]
Statement [Table]
Summary of Stock Option Activity
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Document Fiscal Period Focus
Document Fiscal Period Focus
Lessee, Operating Lease, Liability, to be Paid
Total undiscounted operating lease payments
Amount of total debt available.
Debt Total Available
Amount of total debt available
Investment, Policy [Policy Text Block]
Investments
2025
Lessee, Operating Lease, Liability, to be Paid, Year Two
Statement [Line Items]
Statement [Line Items]
Term Loan
Term Loan [Member]
Term loan.
U.S. government treasury securities
Us Government Treasury Security [Member]
Us government treasury security.
Debt Instrument, Fair Value Disclosure, Total
Estimated fair value of term loan
Debt Instrument, Fair Value Disclosure
Potential dilutive securities excluded from diluted net loss per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Manufacturing Machinery and Equipment
Machinery and Equipment [Member]
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Standard Warrants
Common Stock Warrant
Warrant
Long-Term Debt, Corporate Bond Securities Member
Long-Term Debt, Corporate Bond Securities [Member]
Long Term Debt Corporate Bond Securities Member
Schedule of Significant Components of Net Deferred Tax Assets and Liabilities
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Research and development arrangement, costs incurred
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross
Common Stock
Common Stock [Member]
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Schedule of Accrued Expenses and Other Current Liabilities
Schedule of Accrued Expenses and Other Current Liabilities [Table Text Block]
Schedule of accrued expenses and other current liabilities.
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Total
Cash and cash equivalents
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Summary of Stock-Based Compensation Expense Related to Stock Options, RSUs and ESPP
Other Assets, Current
Other current assets
Cash and Cash Equivalent Member.
Cash and Cash Equivalent [Member]
Cash And Cash Equivalent Member
Net amortization (accretion) of premium/discount on available-for-sale securities
Accretion (Amortization) of Discounts and Premiums, Investments
Prepaid Expense, Current, Total
Prepaid Expense, Current
Prepaid expenses
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Jefferies LLC.
Jefferies LLC [Member]
Jefferies LLC
Registration Payment Arrangement, Arrangement [Domain]
Cover
Cover [Abstract]
Vesting
Vesting [Axis]
Document Fiscal Year Focus
Document Fiscal Year Focus
Lilly license agreement member.
Lilly License Agreement [Member]
Lilly License Agreement
Sale of Stock
Sale of Stock [Domain]
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Weighted average fair value of RSUs granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value Per Share, Granted
Restructuring Plan [Domain]
Defined Contribution Plan, Administrative Expense
Employer contribution plan expense incurred
Security Exchange Name
Security Exchange Name
Federal
Domestic Tax Authority [Member]
Recently Accounting Pronouncements Adopted
New Accounting Pronouncements, Policy [Policy Text Block]
Preferred Stock, Shares Issued, Total
Preferred stock, shares issued
Preferred Stock, Shares Issued
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Change in state apportionment - deferred tax impact
Effective Income Tax Rate Reconciliation, Change in Enacted Tax Rate, Percent
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Shares, Vested
Shares, Vested
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Pre-Funded Warrants
Right-of-use assets recognized in exchange for lease liabilities
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Realignment Plan
Realignment Plan Member
Realignment plan.
Forfeited, Weighted-Average Exercise Price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Legal Entity [Axis]
Legal Entity
Financial Instrument [Axis]
Accrued compensation and benefits
Accrued Employee Benefits, Current
Summary of RSU Activity
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Exercise of common stock options
Stock Issued During Period, Value, Stock Options Exercised
Entity Emerging Growth Company
Entity Emerging Growth Company
Aggregate intrinsic value of options exercised
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Redeemable convertible preferred stock converted into common stock
Redeemable convertible preferred stock converted into common stock
Convertible Preferred Stock, Shares Issued upon Conversion
Amendment Flag
Amendment Flag
Tax credit carryforward, amount
Tax Credit Carryforward, Amount
General Business Tax Credit Carryforward [Member]
General Business Tax Credit Carryforward
Initial Public Offering
IPO [Member]
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Gross Unrealized Losses
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Deferred tax liabilities:
Deferred Tax Liabilities, Gross [Abstract]
Leases [Abstract]
Variable Rate
Variable Rate [Domain]
Exercise of pre-funded warrants, Shares
Exercise of Pre-funded Warrants, Shares
Number of pre-funded warrants exercised.
Debt Securities, Available-for-Sale, Unrealized Loss Position
Fair value, total
Fair value, total
Entity File Number
Entity File Number
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total gross deferred tax assets
Deferred Tax Assets, Gross
Vested and exercisable, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Long-term Debt, Excluding Current Maturities, Total
Term loan, net of current portion
Long-Term Debt, Excluding Current Maturities
Unrealized gain (loss) on available for sale securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Total cash, cash equivalents and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Cash, cash equivalents, and restricted cash at beginning of period
Cash, cash equivalents, and restricted cash at end of period
Share-Based Payment Arrangement [Abstract]
Estimated Shares Issuable Under Employee Stock Purchase Plan [Member]
Estimated shares issuable under the employee stock purchase plan.
Estimated shares issuable under the ESPP
Accounts Payable, Current, Total
Accounts payable
Accounts Payable, Current
Debt Instrument
Debt Instrument [Axis]
Deferred Tax Assets, Valuation Allowance, Total
Deferred Tax Assets, Valuation Allowance
Valuation allowance
Total operating expenses
Operating Expenses
2024
Long-Term Debt, Maturity, Year One
Auditor Location
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Entity Address, Address Line Two
Entity Address, Address Line Two
Schedule Of Defined Benefit Plans Disclosures [Table]
Schedule of Defined Benefit Plans Disclosures [Table]
Intangible assets
Deferred Tax Assets, Goodwill and Intangible Assets
Preferred stock, $0.0001 par value; 10,000,000 shares authorized and no shares issued or outstanding as of December 31, 2023 and 2022
Preferred Stock, Value, Issued, Ending Balance
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued
Entity Small Business
Entity Small Business
Entity Shell Company
Entity Shell Company
Number of operating segment
Number of Operating Segments
Title of Individual [Axis]
Warrants exercise price
Class of Warrant or Right, Exercise Price of Warrants or Rights
Purchases of investments
Purchases of investments
Payments to Acquire Investments
Payments to Acquire Investments, Total
Class of Warrant or Right
Class of Warrant or Right [Domain]
Deferred tax assets capitalized research and experimental costs.
Deferred Tax Assets Capitalized Research And Experimental Costs
Capitalized research and experimental costs
Restricted Stock, Shares Issued Net of Shares for Tax Withholdings
Issuance of common stock related to vesting of restricted stock units, net of tax withholdings,shares
Net Loss Per Share
Earnings Per Share [Text Block]
Entity Address, Address Line One
Entity Address, Address Line One
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Percentage of incentive stock options granted
Percentage Of Incentive Stock Options Granted
Percentage of incentive stock options granted.
Antidilutive Securities
Antidilutive Securities [Axis]
Common stock capital shares reserved for future issuance.
Common Stock Capital Shares Reserved For Future Issuance Table [Text Block]
Summary of Common Stock Reserved for Future Issuance
Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Restricted Cash, Total
Restricted cash
Restricted Cash
Performance Based Vesting
Share Based Compensation Award Tranche Four [Member]
Share Based Compensation Award Tranche Four [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Weighted Average Grant Date Fair Value Per Share, Beginning Balance
Weighted Average Grant Date Fair Value Per Share, Ending Balance
The cash inflow from the issuance of common stock and warrants.
Proceeds from Issuance of Common Stock and Warrants
The cash inflow from the issuance of common stock and warrants.
Subsequent Event Type
Subsequent Event Type [Domain]
Income Statement Location
Income Statement Location [Axis]
2026
Long-Term Debt, Maturity, Year Three
Restricted Stock, Value, Shares Issued Net of Tax Withholdings
Issuance of common stock related to vesting of restricted stock units, net of tax withholdings
Computer and Office Equipment
Computer And Office Equipment [Member]
Computer and office equipment.
Expected dividend rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
2028
Lessee, Operating Lease, Liability, to be Paid, Year Five
Fair Value Non-recurring
Fair Value, Nonrecurring [Member]
Level 2
Fair Value, Inputs, Level 2 [Member]
Exercise of pre-funded warrants
Exercise of Pre-funded Warrants
Value of pre-funded warrants exercised.
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Long-Term Debt, Gross
Term loan, gross
Term loan, gross
Term loan, gross
Title of 12(b) Security
Title of 12(b) Security
Prime Rate
Prime Rate [Member]
Maximum percentage of compensation that an employee is allowed to purchase shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Summary of Financial Assets Measured at Fair Value on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent, Total
Nondeductible expenses
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Cash flows from investing activities
Net Cash Provided by (Used in) Investing Activities [Abstract]
State
State and Local Jurisdiction [Member]
Segment Reporting
Segment Reporting, Policy [Policy Text Block]
Long-Lived Tangible Asset [Domain]
Subsequent Event [Table]
Subsequent Event [Table]
Restricted Cash
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Land Subject to Ground Leases
Area of office space
Time Based Vesting Installments Through June 30, 2023
Share-Based Payment Arrangement, Tranche Three [Member]
Unrecognized cash deposit collateral.
Unrecognized Cash Deposit Collateral
Collateralized by a restricted cash deposit
Equity incentive plans terms
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Gross unrealized losses, total
Gross unrealized losses, total
Restructuring Plan [Axis]
Silicon Valley Bank
Silicon Valley Bank [Member]
Silicon valley bank.
Common stock, shares outstanding
Balance, Shares
Balance, Shares
Common Stock, Shares, Outstanding
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Share-Based Payment Arrangement [Text Block]
Stock-Based Compensation
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Weighted Average Grant Date Fair Value Per Share, Forfeited
Comprehensive loss
Comprehensive Loss PolicyTextBlock
Comprehensive Loss
Supplemental cash flow data:
Supplemental Cash Flow Elements [Abstract]
Proceeds from exercise of pre-funded warrants
Proceeds from Warrant Exercises
Right-of-use assets
Lease Right of Use Asset
Amount of lessee's right to use underlying asset under leases.
Tax Credit Carryforward
Tax Credit Carryforward [Axis]
Unamortized Debt Issuance Expense
Unamortized debt discount and issuance costs
Income Statement Location
Income Statement Location [Domain]
Options granted to purchase shares of common stock, weighted-average exercise price
Granted, Weighted-Average Exercise Price
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Document Type
Document Type
Exercise of shares of common stock related to a cashless exercise of common stock warrant issued in connection with term loan
Net exercised of common stock
Conversion of redeemable convertible preferred stock into common stock upon initial public offering, Shares
Collaboration and license agreement with Kaken Pharmaceutical Co. LTD.
Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD. [Member]
Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD.
Line of Credit Facility, Current Borrowing Capacity
Commitments
Net cash provided by investing activities
Net Cash Provided by (Used in) Investing Activities
Amount of debt available under the second tranche.
Debt Available Second Tranche
Amount of debt available under the second tranche
Counterparty Name
Counterparty Name [Domain]
Organization And Principal Activities [Line Items]
Organization And Principal Activities [Line Items]
Organization and principal activities.
Other
Other
Deferred Tax Liabilities, Other
Net Cash Provided by (Used in) Financing Activities
Net cash provided by (used in) financing activities
Entity Filer Category
Entity Filer Category
Supplemental disclosure of non-cash investing and financing activities:
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Increase (Decrease) in Accrued Liabilities, Total
Increase (Decrease) in Accrued Liabilities
Accrued expenses and other current liabilities
Variable Rate
Variable Rate [Axis]
Short-term investments
Short-Term Investments
Short-term Investments, Total
Deferred Tax Assets, Tax Credit Carryforwards, Total
Tax credits
Deferred Tax Assets, Tax Credit Carryforwards
Total liabilities
Liabilities
Property, Plant and Equipment [Table]
Asset Impairment Charges, Total
Asset Impairment Charges
Impairment losses
Balance
Balance
Equity, Attributable to Parent
Total stockholders' equity
Documents Incorporated by Reference [Text Block]
Documents Incorporated by Reference
Net loss
Net loss
Net Income (Loss)
Interest Expense, Total
Interest expense
Interest Expense
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
State income tax, net of federal benefit
Corporate Debt Securities [Member]
Corporate bonds
Fair Value of Financial Instruments
Fair Value Measurement, Policy [Policy Text Block]
Statement of Financial Position [Abstract]
Weighted Average Number of Shares Outstanding, Diluted, Total
Weighted Average Number of Shares Outstanding, Diluted
Weighted-average shares of common stock outstanding,diluted
Employee stock purchase plan offering period
Employee Stock Purchase Plan Offering Period
Employee stock purchase plan offering period.
Schedule of Reconciliation of the Federal Statutory Income Tax Rate to Effective Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Effective tax rate
Effective Income Tax Rate Reconciliation, Percent
All Other Options
All Other Options [Member]
All other options.
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total
Accruals
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals
Debt Securities, Available-for-Sale, Amortized Cost
Amortized Cost
Amortized Cost
Operating Lease, Weighted Average Remaining Lease Term
Weighted average remaining lease term (years)
Purchase price of common stock expressed as a percentage of fair market value
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Income Taxes
Income Tax Disclosure [Text Block]
Interest and Other Income
Interest and other income, net
Beginning Balance, Weighted-Average Exercise Price
Ending Balance, Weighted-Average Exercise Price
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
End of term payment, amount
End Of Term Payment Amount
End of term payment, amount.
401(K) Plan
Four Zero One K Plan [Member]
Four zero one k plan.
Schedule of Computation of Basic and Diluted Net Loss Per Share
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Leasehold Improvements
Leasehold Improvements [Member]
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Gross unrealized losses, twelve months or greater
Income Tax Authority
Income Tax Authority [Axis]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Fair Value Disclosures [Abstract]
Fair Value Hierarchy and NAV [Axis]
Measurement Frequency
Measurement Frequency [Domain]
Percentage of Exercise price of incentive stock options granted owns stock
Percentage Of Exercise Price Of Incentive Stock Options Granted Owns Stock
Percentage of exercise price of incentive stock options granted owns stock.
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Redeemable Convertible Preferred Stock
Redeemable Convertible Preferred Stock [Member]
RSUs granted
Shares, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted
Initial public offering of common stock
Initial public offering of common stock, net of underwriting expenses and offering costs of $10,149, Shares
Stock Issued During Period, Shares, New Issues
Potential additional cash receipt
Potential Additional Cash Receipt
Potential additional cash receipt.
Deferred revenue
Deferred Revenue, Current
Deferred Revenue, Current, Total
Class of Warrant or Right
Class of Warrant or Right [Axis]
Income Tax Disclosure [Abstract]
Tax Credit Carryforward, Name
Tax Credit Carryforward, Name [Domain]
Operating Loss Carryforwards, Total
Net operating loss carryforwards
Operating Loss Carryforwards