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Weighted Average Remaining Contractual Term Maturities Available For Sale Weighted-average remaining contractual term maturities available for sale City Area Code City Area Code Liabilities, Current Total current liabilities Common stock capital shares reserved for future issuance. Common Stock Capital Shares Reserved For Future Issuance Table [Text Block] Summary of Common Stock Reserved for Future Issuance Net Cash Provided by (Used in) Operating Activities, Continuing Operations Cash in operations Net Cash Provided by (Used in) Operating Activities, Continuing Operations, Total Share Based Compensation Award Tranche Four Share Based Compensation Award Tranche Four [Member] Share Based Compensation Award Tranche Four [Member] Proceeds from issuance of common stock and warrants Proceeds from Issuance of Common Stock and Warrants The cash inflow from the issuance of common stock and warrants. Stock Issued During Period, Shares, Conversion of Convertible Securities Net exercised of common stock Organization, Consolidation and Presentation of Financial Statements [Abstract] Local Phone Number Local Phone Number Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] Gross unrealized losses, less than twelve months Gross unrealized losses, less than twelve months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss Issuance of common stock related to vesting of restricted stock units, net of tax withholdings, shares Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Proceeds from exercise of pre-funded warrants Proceeds from Warrant Exercises Commitments and Contingencies Disclosure [Abstract] Exercise of Pre-funded Warrants Exercise of Pre-funded Warrants Value of pre-funded warrants exercised. Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Cash equivalents and available for sale securities, amortized cost Cash equivalents and investments securities, Amortized Cost Interest rate of term loan Debt Instrument, Interest Rate, Stated Percentage Retained Earnings [Member] Accumulated Deficit Document Transition Report Document Transition Report Increase (Decrease) in Other Operating Assets Other assets Increase (Decrease) in Other Operating Assets, Total Antidilutive Security, Excluded EPS Calculation [Table] Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table] Proceeds from issuance of common stock related to employee stock purchase plan Proceeds from Stock Plans Concentration Risk, Credit Risk, Policy [Policy Text Block] Concentration of Credit Risk Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net, Total Less: unamortized debt issuance costs Minimum [Member] Minimum Common Stock [Member] Common Stock Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Long-Term Debt, Maturity, Year Two 2025 Research and development arrangement, costs incurred Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross Additional Paid-in Capital [Member] Additional Paid-In Capital Debt instrument, extended term. Debt Instrument Extended Term Debt instrument, extended term Cash equivalents and short term investments due term. Cash Equivalents And Short Term Investments Due Term Cash equivalents and short term investments due term Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net loss to net cash used in operating activities: Other Comprehensive Income (Loss), Net of Tax [Abstract] Other comprehensive gain, net of tax: Statement of Income Location, Balance [Domain] Income Statement Location Other Assets, Noncurrent Other assets Other Assets, Noncurrent, Total Silicon valley bank. Silicon Valley Bank [Member] Silicon Valley Bank Increase (Decrease) in Other Operating Liabilities Other liabilities Increase (Decrease) in Other Operating Liabilities, Total Other Assets, Current Other current assets Amount of lessee's right to use underlying asset under leases. Right-of-use assets Lease Right of Use Asset Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Lessee operating lease termination date. Lessee Operating Lease Termination Date Short term lease terminated Fair value, less than twelve months Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD. [Member] Collaboration and license agreement with Kaken Pharmaceutical Co. LTD. Basis of Presentation Basis of Accounting, Policy [Policy Text Block] Allowance for credit losses Debt Securities, Available-for-Sale, Allowance for Credit Loss Debt Securities, Available-for-Sale, Allowance for Credit Loss, Ending Balance Debt Securities, Available-for-Sale, Allowance for Credit Loss, Beginning Balance Debt Securities, Available-for-Sale, Allowance for Credit Loss, Total Amount of debt available under the second tranche. Debt Available Second Tranche Amount of debt available under the second tranche Common stock, $0.0001 par value; 200,000,000 shares authorized as of June 30, 2024 and December 31, 2023; 41,302,599 and 41,029,832 shares issued and outstanding as of June 30, 2024 and December 31, 2023, respectively Common Stock, Value, Issued Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Collaborative Arrangement and Arrangement Other than Collaborative [Line Items] Organization and principal activities. Organization And Principal Activities [Line Items] Organization And Principal Activities [Line Items] Cash equivalents and available for sale securities, amortized cost Cash and Cash Equivalents, Fair Value Disclosure Cash and cash equivalents, fair value Cash equivalents, fair value Fair Value, Assets Measured on Recurring Basis [Table Text Block] Summary of Financial Assets Measured at Fair Value on Recurring Basis Long-Term Debt, Maturity, Year Three 2026 Debt securities, available-for-sale, realized gain (loss), excluding other-than-temporary impairment Impairment loss on investments Available for Sale securities Impairment loss on investments available for sale securities. Operating Lease, Liability, Total Operating Lease, Liability Total operating lease liability Measurement Frequency [Axis] Measurement Frequency Schedule of Accrued Liabilities [Table Text Block] Commitments and contingencies Commitments and Contingencies Gross unrealized losses, twelve months or greater Gross unrealized losses, twelve months or greater Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss Weighted-average shares of common stock outstanding, diluted Weighted-average shares of common stock outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted, Total Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Research and Development Arrangement, Contract to Perform for Others, Type [Axis] Lessee, Operating Lease, Renewal Term Operating leases, renew lease term HMNC Agreement HMNC Agreement [Member] HMNC agreement. Entity Small Business Entity Small Business Securities Purchase Agreement Securities Purchase Agreement [Member] Securities Purchase Agreement [Member] Debt Disclosure [Text Block] Term Loan Collaboration revenue Revenues Revenues, Total Investments, Fair Value Disclosure, Total Investments, Fair Value Disclosure Investments Additional aggregate license agreement amount. Additional Aggregate License Agreement Amount Additional aggregate license agreement amount Accretion (Amortization) of Discounts and Premiums, Investments Net accretion of discount on available-for-sale securities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities Weighted Average Number of Shares Outstanding Reconciliation [Abstract] Denominator: End of term payment, amount. End Of Term Payment Amount End of term payment, amount Measurement Frequency [Domain] Measurement Frequency Fair Value, Inputs, Level 3 [Member] Level 3 Operating Lease, Weighted Average Remaining Lease Term Weighted-average remaining lease term for operating leases Subsequent Events [Text Block] Subsequent Events Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Potential additional cash receipt. Potential Additional Cash Receipt PotentialAdditionalCashReceipt Liabilities fair value Liabilities, Fair Value Disclosure Liabilities, Fair Value Disclosure, Total Accrued expenses and other current liabilities Increase (Decrease) in Accrued Liabilities Increase (Decrease) in Accrued Liabilities, Total Short-Term Lease, Cost Short-term lease expense