Entity Address, City or Town
Entity Address, City or Town
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Schedule of Reconciliation of the Federal Statutory Income Tax Rate to Effective Tax Rate
Entity Ex Transition Period
Entity Ex Transition Period
Fair Value Disclosures [Abstract]
Earnings Per Share [Abstract]
Fair Value, Inputs, Level 1 [Member]
Level 1
Schedule of Accrued Liabilities [Table Text Block]
Schedule of Accrued Expenses and Other Current Liabilities
Domestic Tax Authority [Member]
Federal
Returned the letter of credit
Letter of Credit Returned
Letter of credit returned.
Deferred Tax Assets, Gross [Abstract]
Deferred tax assets:
Research and Development Expense, Policy [Policy Text Block]
Research and Development Expenses
Net Cash Provided by (Used in) Financing Activities [Abstract]
Cash flows from financing activities
Net decrease in cash, cash equivalents, and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Excluding Exchange Rate Effect
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Expected dividend rate
Shelf Registration And Sales Agreement
Shelf Registration and Sales Agreement [Member]
Shelf Registration and Sales Agreement.
Accrued interest on investments
Accrued Investment Income Receivable
Amendment Flag
Amendment Flag
Eli Lilly and company.
Eli Lilly And Company [Member]
Eli Lilly and Company
2026
Long-Term Debt, Maturity, Year Four
Options vested in period, fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested in Period, Fair Value
Subsequent Event Type [Domain]
Subsequent Event Type
Research and Development [Abstract]
Accrued expenses and other current liabilities
Accrued Expenses and Other Current Liabilities
Accrued expenses and other current liabilities.
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Operating lease right-of-use asset
Operating Lease, Right-of-Use Asset
Accrued research and development expenses.
Accrued Research And Development Expenses Policy [Text Block]
Accrued Research and Development Expenses
Schedule of Long-Term Debt Instruments [Table]
Debt Instrument [Table]
Share-Based Payment Arrangement, Employee [Member]
Stock Option Granted to Executive Officers
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
Less: present value discount
Earnings Per Share, Policy [Policy Text Block]
Net Loss per Share
Number of shares issuable upon the exercise of warrant
Number Of Shares Issuable Upon Exercise Of Warrants
Number of shares issuable upon exercise of warrants.
Percentage of outstanding shares subject to automatic increase in common stock.
Percentage Of Outstanding Shares Subject To Automatic Increase In Common Stock
Percentage of outstanding shares subject to automatic increase in common stock
Statement [Table]
Statement [Table]
Operating lease liability, net of current portion
Operating lease liability, net of current portion
Operating Lease, Liability, Noncurrent
Threshold percentage of tax positions likely of being realized upon ultimate settlement.
Threshold Percentage Of Tax Positions Likely Of Being Realized Upon Ultimate Settlement
Percentage of tax positions likely of being realized upon ultimate settlement
Cash paid for operating lease liabilities
Operating Lease, Payments
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Issuance of common stock related to employee stock purchase plan,shares
ESPP issued
Number of Operating Segments
Number of operating segment
Preferred Stock, Shares Outstanding
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred Stock, Shares Outstanding, Ending Balance
Machinery and Equipment [Member]
Manufacturing Machinery and Equipment
Common Stock, Capital Shares Reserved for Future Issuance
Shares reserved for future issuance
Auditor Firm ID
Weighted Average Grant Date Fair Value Per Share, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Two thousand and sixteen equity incentive plan.
Two Thousand And Sixteen Equity Incentive Plan [Member]
2016 Equity Incentive Plan
Registration Payment Arrangement, Arrangement [Domain]
Share-based compensation arrangement by share-based payment award, options, early exercised, shares.
Share Based Compensation Arrangement By Share Based Payment Award Options Early Exercised Shares
Number of shares early exercised under any plan
Income Tax Authority [Domain]
Income Tax Authority
Deferred Tax Assets, Tax Credit Carryforwards
Tax credits
Deferred Tax Assets, Tax Credit Carryforwards, Total
Accounting Standards Update 2019-12 [Member]
Topic 740
Employee Stock [Member]
Employee Stock Purchase Plan, Available for Future Issuance
Organization and principal activities.
Organization And Principal Activities [Table]
Organization And Principal Activities [Table]
Lessee, Operating Leases [Text Block]
Leases
Estimated fair value of the warrant
Estimated Fair Value Of Warrant
Estimated fair value of warrant.
Share-Based Payment Arrangement, Option [Member]
Stock Option
Stock Options, Issued and Outstanding
Registration Payment Arrangement by Arrangement [Axis]
Weighted average remaining lease term (years)
Operating Lease, Weighted Average Remaining Lease Term
Total liabilities and stockholders' equity
Liabilities and Equity
Plan Name [Domain]
Plan Name
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Income Statement [Abstract]
Short Term Debt Commercial Paper Member
Short-Term Debt, Commercial Paper [Member]
Short-Term Debt, Commercial Paper Member.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price
Vested and exercisable, Weighted-Average Exercise Price
Share-Based Payment Arrangement, Tranche Three [Member]
Time Based Vesting Installments Through June 30, 2023
Organization, Consolidation and Presentation of Financial Statements Disclosure [Text Block]
Organization and Principal Activities
Total gross proceeds
Proceeds from Stock Plans
Proceeds from issuance of common stock related to employee stock purchase plan
Sale of Stock [Domain]
Sale of Stock
Liabilities, Current
Total current liabilities
Probable of Achievement
Probable Of Achievement [Member]
Probable of achievement member.
Stock Issued During Period, Value, Employee Stock Purchase Plan
Issuance of common stock related to employee stock purchase plan
Operating Loss Carryforwards
Net operating loss carryforwards
Operating Loss Carryforwards, Total
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent
Nondeductible expenses
Effective Income Tax Rate Reconciliation, Nondeductible Expense, Percent, Total
2025
Lessee, Operating Lease, Liability, to be Paid, Year Three
Recent accounting pronouncements not yet adopted.
Recent Accounting Pronouncements Not Yet Adopted Policy [Text Block]
Recent Accounting Pronouncements Not Yet Adopted
Series B redeemable convertible preferred stock.
Series B Redeemable Convertible Preferred Stock [Member]
Series B Redeemable Convertible Preferred Stock
Fair Value, Recurring [Member]
Fair Value Recurring
Interest Expense
Interest expense
Interest Expense, Total
Share-Based Payment Arrangement, Tranche Two [Member]
Monthly Anniversary
Income Tax, Policy [Policy Text Block]
Income Taxes
Income tax disclosure table.
Income Tax Disclosure [Table]
Income Tax Disclosure [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Maximum Employee Subscription Rate
Maximum percentage of compensation that an employee is allowed to purchase shares
Preferred Stock, Shares Authorized
Preferred stock, shares authorized
Number of Monthly Installments
Number Of Monthly Installments
Number of monthly installments.
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Weighted average discount rate
Operating Lease, Weighted Average Discount Rate, Percent
Variable Rate [Axis]
Variable Rate
Entity Small Business
Entity Small Business
Cash, cash equivalents, and restricted cash at end of period
Cash, cash equivalents, and restricted cash at beginning of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents
Total cash, cash equivalents and restricted cash
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Collaborative Arrangement and Arrangement Other than Collaborative
Share based compensation arrangement by share based payment award maximum term.
Share Based Compensation Arrangement By Share Based Payment Award Maximum Term
Equity incentive plan, maximum term
Risks and uncertainties..
Risks And Uncertainties Policy [Text Block]
Risks and Uncertainties
Assets, Current
Total current assets
Property, Plant and Equipment [Line Items]
Weighted-average shares of common stock outstanding, basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
City Area Code
City Area Code
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Aggregate Intrinsic Value
Money Market Fund Member
Money Market Fund [Member]
Money Market Fund Member.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Forfeited/Cancelled, Outstanding Stock Options
Share-Based Payment Arrangement [Abstract]
Liabilities
Total liabilities
Document Period End Date
Document Period End Date
Less: interest
Debt Interest
Total interest under term loan.
Share-Based Payment Arrangement, Nonemployee [Member]
Stock Options Granted to Nonemployees
Tax credit carryforward expiration year.
Tax Credit Carryforward Expiration Year
Tax credit carryforward expiration year
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Weighted-average fair value of options granted
Lessee, Operating Lease, Renewal Term
Operating leases, renew lease term
Amortized Cost
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Share-Based Payment Arrangement, Tranche One [Member]
First Anniversary
Clinical Development Milestones
Clinical Development Milestones [Member]
Clinical development milestones member.
Statistical Measurement [Axis]
Statistical Measurement
Fair value, less than twelve months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Other current assets
Other Assets, Current
Subsequent Event [Line Items]
Subsequent Event [Line Items]
Product manufacture milestones payments
Product Manufacture Milestones Payments
Product manufacture milestones payments.
Assets
Total assets
Accounting Standards Update 2016-02 [Member]
Topic 842
Issuance of common stock related to vesting of restricted stock units, net of tax withholdings
Restricted Stock, Value, Shares Issued Net of Tax Withholdings
Conversion of redeemable convertible preferred stock into common stock upon initial public offering, Shares
Net exercised of common stock
Exercise of shares of common stock related to a cashless exercise of common stock warrant issued in connection with term loan
State and Local Jurisdiction [Member]
State
Software Development [Member]
Computer Software
Share based compensation arrangement by share based payment award options termination term if option holders service terminate.
Share Based Compensation Arrangement By Share Based Payment Award Options Termination Term If Option Holders Service Terminate
Options termination term, if option holders service terminate
Long-Term Debt, Excluding Current Maturities
Term loan, net of current portion
Long-term Debt, Excluding Current Maturities, Total
Net loss per share,diluted
Earnings Per Share, Diluted
Earnings Per Share, Diluted, Total
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Schedule of Potentially Dilutive Securities not Included in Calculation of Diluted Per Share
Share-based compensation arrangement by share-based payment award, term of automatically increase in common stock available for issuance.
Share Based Compensation Arrangement By Share Based Payment Award Term Of Automatically Increase In Common Stock Available For Issuance
Term of automatically increase in common stock available for issuance
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
Document Fiscal Period Focus
Document Fiscal Period Focus
First tranche term loan.
First Tranche Term Loan [Member]
First Tranche Term Loan
Restricted Cash
Restricted cash
Restricted Cash, Total
Valuation allowance
Deferred Tax Assets, Valuation Allowance
Deferred Tax Assets, Valuation Allowance, Total
Preferred stock, $0.0001 par value; 10,000,000 shares authorized and no shares issued or outstanding as of December 31, 2022 and 2021
Preferred Stock, Value, Issued
Preferred Stock, Value, Issued, Total
Preferred Stock, Value, Issued, Beginning Balance
Preferred Stock, Value, Issued, Ending Balance
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Stock-based compensation
APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total
Common stock purchasable under warrants
Common Stock Purchasable Under Warrants
Common stock purchasable under warrants.
Deferred Tax Liabilities, Gross [Abstract]
Deferred tax liabilities:
Daly City, California
Daly City, California [Member]
Daly City, California.
Counterparty Name [Domain]
Counterparty Name
Total operating lease liability
Operating Lease, Liability
Lease liability
Net cash provided by (used in) financing activities
Net Cash Provided by (Used in) Financing Activities
Total minimum rental payments
Operating Leases, Future Minimum Payments Due
Statement of Financial Position [Abstract]
Entity File Number
Securities Act File Number
Statement of Cash Flows [Abstract]
Maximum amount of sale covered in shelf registration statement
Maximum Amount Of Sale Covered In Shelf Registration Statement
Maximum amount of sale cCovered in shelf registration statement.
Thereafter
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Proceeds from maturities of investments
Proceeds from Sale, Maturity and Collection of Investments
Proceeds from Sale, Maturity and Collection of Investments, Total
Commitments
Line of Credit Facility, Current Borrowing Capacity
Operating lease right-of-use asset
Deferred tax liabilities right-of-use assets.
Deferred Tax Liabilities Right-of-use Assets
Retirement Benefits [Text Block]
401(k) Retirement Savings Plan
Geographical [Domain]
Statistical Measurement [Domain]
Statistical Measurement
Statement of Stockholders' Equity [Abstract]
Sale of Stock [Axis]
Sale of Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Purchase price of common stock expressed as a percentage of fair market value
Auditor Location
Class of Stock [Domain]
Class of Stock
Accrued general and administrative expenses.
Accrued General And Administrative Expenses
Accrued general and administrative expenses
Legal Entity
Legal Entity [Axis]
Other Information Related to Operating Leases
Lease, Cost [Table Text Block]
Subsequent Events [Abstract]
Fair Value Disclosures [Text Block]
Fair Value Measurements
Proceeds from Stock Options Exercised
Proceeds from exercise of common stock options
Proceeds from Issuance of Common Stock
Net proceeds of common stock
Fair market value exercise price percentage.
Fair Market Value Exercise Price Percentage
Fair market value exercise price percentage
Grantee Status [Axis]
Grantee Status
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Concentration of Credit Risk
Second tranche term loan.
Second Tranche Term Loan [Member]
Second Tranche Term Loan
Antidilutive Securities [Axis]
Antidilutive Securities
Preferred Stock, Par or Stated Value Per Share
Preferred Stock, Par Value
Gross Unrealized Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Lessee, Lease, Description [Line Items]
Cash, cash equivalents, and short-term investments
Cash, Cash Equivalents, and Short-Term Investments
Cash, Cash Equivalents, and Short-Term Investments, Total
Supplemental Balance Sheet Disclosures [Text Block]
Balance Sheet Components
Subsequent Events [Text Block]
Subsequent Events
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Weighted-average shares of common stock outstanding,diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Corporate bonds
Corporate Debt Securities [Member]
General and Administrative Expense [Member]
General and Administrative
Convertible Preferred Stock, Shares Issued upon Conversion
Redeemable convertible preferred stock converted into common stock
Redeemable convertible preferred stock converted into common stock
Incentive stock options granted description.
Incentive Stock Options Granted Description
Incentive stock options granted description
Net Cash Provided by (Used in) Operating Activities, Continuing Operations
Cash in operations
Net Cash Provided by (Used in) Operating Activities, Continuing Operations, Total
Current Fiscal Year End Date
Current Fiscal Year End Date
Financial Instruments [Domain]
Shares subject to outstanding common stock options.
Shares Subject To Outstanding Common Stock Options [Member]
Shares Subject to Outstanding Common Stock Options
Other Assets, Noncurrent
Other assets
Other Assets, Noncurrent, Total
Entity Address, Address Line One
Entity Address, Address Line One
Repayments of Long-term Debt, Total
Repayments of Long-Term Debt
Repayment of term loan
Repayment of term loan
Operating loss carryforwards expiration year.
Operating Loss Carryforwards Expiration Year
Net operating loss carryforwards expiration year
Document Annual Report
Document Annual Report
Schedule of Weighted-Average Assumptions to Estimate Fair Value of Stock Options and Purchase Rights Under ESPP Using the Black-Scholes Option-Pricing Model
Schedule of Share-Based Payment Award, Employee Stock Purchase Plan, Valuation Assumptions [Table Text Block]
Investments
Investment, Policy [Policy Text Block]
Restricted cash, long-term (included in other assets)
Restricted Cash, Noncurrent
Income Tax Expense (Benefit)
Income tax expense
Income Tax Expense (Benefit), Total
Income Tax Disclosure [Text Block]
Income Taxes
Vesting [Axis]
Vesting
Preferred Stock, Shares Issued
Preferred stock, shares issued
Preferred Stock, Shares Issued, Total
Payments to Acquire Property, Plant, and Equipment
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment, Total
Income Tax Disclosure [Abstract]
Stock Issued During Period, Shares, New Issues
Initial public offering of common stock, net of underwriting expenses and offering costs of $10,149, Shares
Initial public offering of common stock
Maximum amount of offering issuance and sale covered in sales agreement
Registration Payment Arrangement, Maximum Potential Consideration
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals
Accruals
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total
Amount of debt available under the first tranche
Debt Available First Tranche
Amount of debt available under the first tranche.
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Other
Fair Value Hierarchy and NAV [Axis]
Shares available for future issuance under two thousand and twenty equity incentive plan.
Shares Available For Future Issuance Under Two Thousand And Twenty Equity Incentive Plan [Member]
Shares available for future issuance under 2020 Equity Incentive Plan
Share-Based Payment Arrangement [Policy Text Block]
Stock-Based Compensation
Auditor Name
Equity [Abstract]
Issuance of common stock related to vesting of restricted stock units, net of tax withholdings,shares
Restricted Stock, Shares Issued Net of Shares for Tax Withholdings
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Forfeited/Cancelled, Weighted-Average Exercise Price
Operating lease liability, net of current portion and other liabilities
Increase (Decrease) in Other Noncurrent Liabilities
Operating Income (Loss)
Loss from operations
Loss from operations
Interest rate of term loan
Debt Instrument, Interest Rate, Stated Percentage
Lessee, Operating Lease, Option to Extend
Operating Leases, option to renew lease term description
Additional Paid in Capital, Common Stock
Additional paid-in capital
Additional Paid in Capital, Common Stock, Beginning Balance
Additional Paid in Capital, Common Stock, Ending Balance
Balance Sheet Components Disclosure
Balance Sheet Components Disclosure [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award
Equity incentive plans terms
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Unamortized debt discount and issuance costs
Unamortized Debt Issuance Expense
Fair value, total
Fair value, total
Debt Securities, Available-for-Sale, Unrealized Loss Position
Common Stock, Voting Rights
Common stockholders voting rights
Debt securities, available-for-sale, realized gain (loss), excluding other-than-temporary impairment
Debt Securities, Available-for-Sale, Realized Gain (Loss), Excluding Other-than-temporary Impairment
Class of Warrant or Right [Domain]
Class of Warrant or Right
Entity Filer Category
Entity Filer Category
Schedule of common stock shares reserved for future issuance
Schedule Of Common Stock Shares Reserved For Future Issuance Table [TextBlock]
Schedule of common stock shares reserved for future issuance.
Operating Expenses
Total operating expenses
Entity Current Reporting Status
Entity Current Reporting Status
Operating lease termination date
Operating Lease Termination Month And Year
Operatingleaseterminationmonthandyear
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Prime Rate [Member]
Prime Rate
Impairment losses
Asset Impairment Charges
Asset Impairment Charges, Total
Accrued expenses and other liabilities, current.
Accrued Expenses And Other Liabilities Current
Accrued expenses and other current liabilities
Total accrued expenses and other current liabilities
Stockholders' Equity Note Disclosure [Text Block]
Capital Structure
Shares, Vested
Shares, Vested
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Operating lease liability
Deferred Tax Assets Operating Lease Liability
Deferred tax assets operating lease liability.
Total stockholders' equity
Stockholders' Equity Attributable to Parent
Balance
Balance
Gross unrealized losses, total
Gross unrealized losses, total
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total
Debt Securities, Available-for-sale, Realized Gain (Loss), Total
Debt Securities, Available-for-Sale, Realized Gain (Loss)
Debt securities, available-for-sale, realized gain (loss)
AOCI Attributable to Parent [Member]
Accumulated Other Comprehensive Loss
2024
Long-Term Debt, Maturity, Year Two
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Entity Tax Identification Number
Entity Tax Identification Number
Income Statement Location [Axis]
Income Statement Location
Common stock, $0.0001 par value; 200,000,000 shares authorized as of December 31, 2022 and 2021; 23,601,004 and 23,491,881 shares issued and outstanding as of December 31, 2022 and 2021, respectively
Common Stock, Value, Issued
Common Stock, Value, Issued, Total
Common Stock, Value, Issued, Beginning Balance
Common Stock, Value, Issued, Ending Balance
Retained Earnings (Accumulated Deficit)
Accumulated deficit
Retained Earnings (Accumulated Deficit), Total
Retained Earnings (Accumulated Deficit), Beginning Balance
Retained Earnings (Accumulated Deficit), Ending Balance
Equity Components [Axis]
Equity Components
Operating leases termination agreement
Operating Leases Termination Agreement
Operating leases termination agreement.
Less: unamortized debt issuance costs
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net
Debt Instrument, Unamortized Discount (Premium) and Debt Issuance Costs, Net, Total
Accounting Standards Update [Domain]
Income Tax Examination, Penalties and Interest Expense
Income tax penalties or interest
Income Tax Examination, Penalties and Interest Expense, Total
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash and Cash Equivalents
Debt Issuance Costs, Gross
Debt issuance costs
Deferred offering costs included in accrued expenses.
Deferred Offering Costs Included In Accrued Expenses
Deferred offering costs included in accrued expenses
Prepaid expenses
Prepaid Expense, Current
Prepaid Expense, Current, Total
Leases [Abstract]
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Line Items]
Summary Of Significant Accounting Policies [Line Items]
Entity Emerging Growth Company
Entity Emerging Growth Company
Gross unrealized losses, twelve months or greater
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Operating Expenses [Abstract]
Operating expenses:
Emerging growth company policy.
Emerging Growth Company Policy Policy [Text Block]
Emerging Growth Company Status
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number
Vested and exercisable, Outstanding Stock Options
Schedule of Stock by Class [Table]
Schedule Of Stock By Class [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Expected term (in years)
Payments to Acquire Investments, Total
Payments to Acquire Investments
Purchases of investments
Purchases of investments
Debt instrument prepayment fee percentage
Debt Instrument Prepayment Fee Percentage
Debt instrument prepayment fee percentage.
Entity Voluntary Filers
Entity Voluntary Filers
End of term payment, percentage
End Of Term Payment Percentage
End of term payment, percentage.
Floating interest scenario one
Debt Instrument Interest Rate Percentage Scenario One
Debt Instrument Interest Rate Percentage Scenario One
Research and Development Tax Credit Carry Forwards
Research Tax Credit Carryforward [Member]
Retirement Benefits [Abstract]
Depreciation and amortization
Depreciation, Depletion and Amortization, Nonproduction
Depreciation, Depletion and Amortization, Nonproduction, Total
Document Transition Report
Document Transition Report
Floating interest scenario two
Debt Instrument Interest Rate Percentage Scenario Two
Debt Instrument Interest Rate Percentage Scenario Two
2025
Long-Term Debt, Maturity, Year Three
Common stock purchasable under prefunded warrants
Common Stock Purchasable Under Prefunded Warrants
Common stock purchasable under prefunded warrants.
Weighted Average Grant Date Fair Value Per Share, Granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Two thousand and twenty employee stock purchase plan.
Two Thousand And Twenty Employee Stock Purchase Plan [Member]
2020 Employee Stock Purchase Plan
Accrued research and development expenses.
Accrued Research And Development Expenses
Accrued research and development expenses
Two thousand and twenty equity incentive plan.
Two Thousand And Twenty Equity Incentive Plan [Member]
2020 Equity Incentive Plan
Sale of Stock, Price Per Share
Offering price
Collaborative Arrangement Disclosure [Text Block]
License Agreement
Commitments and Contingencies Disclosure [Text Block]
Commitments and Contingencies
Summary of significant accounting policies.
Summary Of Significant Accounting Policies [Table]
Summary Of Significant Accounting Policies [Table]
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Exercised, Weighted-Average Exercise Price
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated Other Comprehensive Income (Loss), Net of Tax
Accumulated other comprehensive loss
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Short Term Debt Corporate Bond Securities Member
Short-Term Debt , Corporate Bond Securities [Member]
Short-Term Debt , Corporate Bond Securities Member.
Long Term Debt Us Treasury Securities Member
Long-Term Debt, US Treasury Securities [Member]
Long-Term Debt, US Treasury Securities Member.
Net Income (Loss) Attributable to Parent
Net loss
Net loss
Operating Lease, Liability, Current, Total
Operating lease liability, current portion
Operating lease liability, current portion
Operating Lease, Liability, Current
Area of office space
Land Subject to Ground Leases
Operating lease commencement date.
Operating Lease Commencement Month And Year
Operating lease commencement date
Additional Paid-in Capital [Member]
Additional Paid-In Capital
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Collaborative Arrangement and Arrangement Other than Collaborative
South San Francisco, California
South San Francisco, California [Member]
South San Francisco, California.
Tax withholding payments on restricted stock units
Payment, Tax Withholding, Share-Based Payment Arrangement
Standard Warrants
Standard Warrants [Member]
Standard warrants.
Deferred Tax Assets, Operating Loss Carryforwards
Net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Total
Schedule of Maturities of Long-Term Debt [Table Text Block]
Schedule of Future Principal Payments
Series A redeemable convertible preferred stock.
Series A Redeemable Convertible Preferred Stock [Member]
Series A Redeemable Convertible Preferred Stock
Series A Redeemable Convertible Preferred Stock
Shares subject to outstanding RSUs
Shares subject to outstanding restricted stock units.
Shares Subject to Outstanding Restricted Stock Units [Member]
Entity Registrant Name
Entity Registrant Name
Liabilities, Fair Value Disclosure, Total
Liabilities, Fair Value Disclosure
Liabilities fair value
Cash and Cash Equivalents, at Carrying Value
Cash and cash equivalents
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value, Total
Cash and Cash Equivalents, at Carrying Value, Beginning Balance
Cash and Cash Equivalents, at Carrying Value, Ending Balance
Earnings Per Share [Text Block]
Net Loss Per Share
Class of Stock [Axis]
Class of Stock
Debt Instrument, Maturity Date
Debt instrument, maturity date
Share-Based Payment Arrangement, Noncash Expense
Stock-based compensation expense
Share-based Payment Arrangement, Noncash Expense, Total
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Vested and expected to vest, Weighted-Average Remaining Contractual Life (Years)
Award Type [Domain]
Award Type
Statement [Line Items]
Statement [Line Items]
Us Treasury Security Member
US Treasury Security [Member]
US Treasury Security Member.
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Vested and expected to vest, Weighted-Average Exercise Price
Title of 12(b) Security
Title of 12(b) Security
Accounts payable
Increase (Decrease) in Accounts Payable
Increase (Decrease) in Accounts Payable, Total
Common Stock [Member]
Common Stock
Cash and Cash Equivalents, Restricted Cash and Cash Equivalents, Policy [Policy Text Block]
Restricted Cash
Net Cash Provided by (Used in) Operating Activities [Abstract]
Cash flows from operating activities
Equity Component [Domain]
Equity Component
Fair Value Measurement, Policy [Policy Text Block]
Fair Value of Financial Instruments
Entity Address, State or Province
Entity Address, State or Province
letter of credit issued
Letter of Credit Issued
Letter of credit issued.
2026
Lessee, Operating Lease, Liability, to be Paid, Year Four
Geographical [Axis]
Income tax disclosure line items.
Income Tax Disclosure [Line Items]
Income Tax Disclosure [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term
Vested and exercisable, Weighted-Average Remaining Contractual Life (Years)
Document Type
Document Type
Interest Paid, Excluding Capitalized Interest, Operating Activities
Cash paid for interest
Schedule of property and equipment useful lives.
Schedule of Property and Equipment Useful Lives [Table Text Block]
Schedule of Useful Lives of Property and Equipment
Entity Shell Company
Entity Shell Company
Restricted and performance stock units, issued and outstanding.
Restricted and Performance Stock Units, Issued and Outstanding [Member]
Restricted and performance stock units, issued and outstanding
Share-Based Payment Arrangement, Expense
Total stock-based compensation expense
Compensation expense
Short-Term Debt [Member]
Short Term Investments
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Recurring and Nonrecurring [Table]
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Amount of total debt available
Debt Total Available
Amount of total debt available.
Security Exchange Name
Security Exchange Name
Term loan.
Term Loan [Member]
Term Loan
Class of Stock [Line Items]
Class Of Stock [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Significant Accounting Policies [Text Block]
Summary of Significant Accounting Policies
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Unrecognized stock-based compensation expense expected to be recognized over weighted-average vesting term
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Weighted-Average Remaining Contractual Life (Years)
Other comprehensive loss, net of tax:
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Commitments and Contingencies Disclosure [Abstract]
Operating lease costs
Operating Lease, Cost
Long Term Debt Corporate Bond Securities Member
Long-Term Debt, Corporate Bond Securities [Member]
Long-Term Debt, Corporate Bond Securities Member
Restricted Stock Units (RSUs) [Member]
RSU
Future Minimum Annual Lease Commitments Under Non-cancelable Operating Leases
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Warrant [Member]
Warrant
Common Stock Warrant
Effective Income Tax Rate Reconciliation, Change in Deferred Tax Assets Valuation Allowance, Percent
Change in valuation allowance
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Summary of Stock Option Activity
New Accounting Pronouncements, Policy [Policy Text Block]
Recently Adopted Accounting Pronouncements
Schedule of Defined Benefit Plans Disclosures [Table]
Schedule Of Defined Benefit Plans Disclosures [Table]
Common Stock, Shares, Outstanding
Balance, Shares
Balance, Shares
Common stock, shares outstanding
Amortization of premium on available-for-sale securities
Accretion (Amortization) of Discounts and Premiums, Investments
Over-Allotment Option [Member]
Overallotment Option
Debt Disclosure [Text Block]
Term Loan
Fair Value, Inputs, Level 2 [Member]
Level 2
Proceeds from Issuance of Long-term Debt, Total
Proceeds from Issuance of Long-term Debt
Proceeds from issuance of term loan, net of issuance costs of $10
Debt Securities, Available-for-Sale
Available for sale securities debt securities
Available for sale, fair value
Available for sale, fair value
Net Cash Provided by (Used in) Investing Activities [Abstract]
Cash flows from investing activities
Cash And Cash Equivalent Member
Cash and Cash Equivalent [Member]
Cash and Cash Equivalent Member.
Increases based on tax positions related to current period
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Commitments and contingencies (Note 7)
Commitments and Contingencies
Common stock, shares sold and issued
Common Stock, Shares, Issued
Common Stock, Shares, Issued, Total
U.S. treasury securities
US Treasury Securities [Member]
Variable Rate [Domain]
Variable Rate
Jefferies LLC
Jefferies LLC [Member]
Jefferies LLC.
Minimum [Member]
Minimum
Lilly License Agreement
Lilly License Agreement [Member]
Lilly license agreement member.
Grantee Status [Domain]
Grantee Status
Restricted cash, short-term (included in other current assets)
Restricted Cash, Current
Lessee, Leases [Policy Text Block]
Leases
Accounting Standards Update [Axis]
Tax Credit Carryforward [Axis]
Tax Credit Carryforward
Weighted Average Grant Date Fair Value Per Share, Ending Balance
Weighted Average Grant Date Fair Value Per Share, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Option, Nonvested, Weighted Average Exercise Price
Debt Instrument [Axis]
Debt Instrument
Stockholders' Equity Attributable to Parent [Abstract]
Stockholders' equity:
State income tax, net of federal benefit
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Clinical and sales milestones payments.
Clinical And Sales Milestones Payments
Milestone payments due
Counterparty Name [Axis]
Counterparty Name
Entity Address, Address Line Two
Entity Address, Address Line Two
Weighted Average Grant Date Fair Value Per Share, Forfeited
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
Award Type [Axis]
Award Type
Subsequent Event [Member]
Subsequent Event
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount
Unrecognized stock-based compensation expense
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Amount, Total
Debt Instrument, Fair Value Disclosure
Estimated fair value of term loan
Debt Instrument, Fair Value Disclosure, Total
Retirement Plan Name [Domain]
Retirement Plan Name
Deferred Tax Assets, Gross
Total gross deferred tax assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period, Intrinsic Value
Aggregate intrinsic value of options exercised
Pre-Funded Warrants
Pre-Funded Warrants [Member]
Pre-Funded Warrants [Member]
Less: term loan, current portion
Long-Term Debt, Current Maturities
Term loan, current portion
Long-term Debt, Current Maturities, Total
Research and Development Expense
Research and development expense
Research and development
Research and Development Expense, Total
Total undiscounted operating lease payments
Lessee, Operating Lease, Liability, to be Paid
Decreases based on tax positions related to current period
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Deferred Tax Assets, Goodwill and Intangible Assets
Intangible assets
Entity Central Index Key
Entity Central Index Key
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Increase in net valuation allowance
Short-term Investments, Total
Short-Term Investments
Short-term investments
Operating leases termination fee payable
Operating Leases Termination Fee Payable
Operating leases termination fee payable.
Net Income (Loss) Attributable to Parent [Abstract]
Numerator:
Accounting Policies [Abstract]
Property, Plant and Equipment [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Expected volatility
Measurement Frequency [Axis]
Measurement Frequency
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Shares remained available for issuance
Stock-Based Compensation
Share-Based Payment Arrangement [Text Block]
Redeemable Convertible Preferred Stock [Member]
Redeemable Convertible Preferred Stock
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Vested and expected to vest, Aggregate Intrinsic Value
Subsequent Event [Table]
Subsequent Event [Table]
General and Administrative Expense
General and administrative
General and Administrative Expense, Total
Employer contribution plan expense incurred
Defined Contribution Plan, Administrative Expense
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Ending Balance, Weighted-Average Exercise Price
Beginning Balance, Weighted-Average Exercise Price
Research and Development Expense [Member]
Research and Development
Fair Value, Nonrecurring [Member]
Fair Value Non-recurring
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Right-of-use assets recognized in exchange for lease liabilities
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Retained Earnings [Member]
Accumulated Deficit
Upfront payment received
Upfront Payment Received
Upfront payment received.
Estimated shares issuable under the ESPP
Estimated shares issuable under the employee stock purchase plan.
Estimated Shares Issuable Under Employee Stock Purchase Plan [Member]
Tax Credit Carryforward, Name [Domain]
Tax Credit Carryforward, Name
Effective Income Tax Rate Reconciliation, Percent
Effective tax rate
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items]
Cash and cash equivalents and available for sale fair value.
Cash And Cash EquivalentsAnd Available For Sale Fair Value
Total cash equivalents, short-term investments and long-term investments
Cash and cash equivalents and available for sale securities, fair value
Total cash equivalents, short term investments and long term investments
Loss on disposal of property and equipment
Gain (Loss) on Disposition of Property Plant Equipment
Gain (Loss) on Disposition of Property Plant Equipment, Total
Fair Value, Balance Sheet Grouping, Financial Statement Captions [Line Items]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Vesting percentage
Entity Interactive Data Current
Entity Interactive Data Current
Tax Credit Carryforward, Amount
Tax credit carryforward, amount
Entity Public Float
Entity Public Float
Total stock options outstanding
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Vested and expected to vest, Outstanding Stock Options
Cash Flow, Noncash Investing and Financing Activities Disclosure [Abstract]
Supplemental disclosure of non-cash investing and financing activities:
Capitalized research and experimental costs
Deferred Tax Assets Capitalized Research And Experimental Costs
Deferred tax assets capitalized research and experimental costs.
2023
Lessee, Operating Lease, Liability, to be Paid, Year One
Weighted Average Remaining Contractual Term Maturities Available For Sale
Weighted-average remaining contractual term maturities available for sale
Weighted-average remaining contractual term maturities available for sale.
Research and Development Arrangement, Contract to Perform for Others, Costs Incurred, Gross
Research and development arrangement, costs incurred
Leasehold Improvements [Member]
Leasehold Improvements
Fair value, twelve months or greater
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Debt securities, available-for-sale, Continuous unrealized loss position, 12 months or longer
Local Phone Number
Local Phone Number
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Federal statutory tax rate
Percentage of incentive stock options granted.
Percentage Of Incentive Stock Options Granted
Percentage of incentive stock options granted
Unrecognized Tax Benefits
Balance at the end of the year
Balance at the beginning of the year
Unrecognized tax benefits
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Summary of Financial Assets Measured at Fair Value on Recurring Basis
Share Based Compensation Award Tranche Four [Member]
Share Based Compensation Award Tranche Four [Member]
Performance Based Vesting
Schedule of Earnings Per Share, Basic and Diluted [Table Text Block]
Schedule of Computation of Basic and Diluted Net Loss Per Share
Long-Term Debt [Member]
Long Term Investments
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Vesting period
Debt Disclosure [Abstract]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Basis of Accounting, Policy [Policy Text Block]
Basis of Presentation
IPO [Member]
Initial Public Offering
Summary of Income Tax Contingencies [Table Text Block]
Schedule of Reconciliation of Beginning and Ending Balance of Unrecognized Tax Benefits
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Granted, Outstanding Stock Options
Options granted to purchase shares of common stock
Other Liabilities, Noncurrent
Other liabilities
Other Liabilities, Noncurrent, Total
Computer and office equipment.
Computer And Office Equipment [Member]
Computer and Office Equipment
Income Statement Location [Domain]
Income Statement Location
2023
Long-Term Debt, Maturity, Year One
Total
Long-Term Debt
Outstanding term loan, after unamortized discount and debt issuance costs
Aggregate principal amount
Prepaid expenses and other current assets
Increase (Decrease) in Prepaid Expense and Other Assets
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Ending Balance, Outstanding Stock Options
Beginning Balance, Outstanding Stock Options
Purchase price of share
Share Price
Debt Instrument, Name [Domain]
Debt Instrument, Name
Document Fiscal Year Focus
Document Fiscal Year Focus
Class of Warrant or Right [Axis]
Class of Warrant or Right
Payments of Debt Issuance Costs
Proceeds from issuance of term loan, issuance costs
2024
Lessee, Operating Lease, Liability, to be Paid, Year Two
Interest and other income, net
Interest and Other Income
Vesting [Domain]
Vesting
Net loss per share, basic
Earnings Per Share, Basic
Earnings Per Share, Basic, Total
Assets [Abstract]
ASSETS
Accrued expenses and other current liabilities
Increase (Decrease) in Accrued Liabilities
Increase (Decrease) in Accrued Liabilities, Total
Reconciliation of cash, cash equivalents, and restricted cash
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract]
Financial Instrument [Axis]
Long-Lived Tangible Asset [Axis]
Liabilities and Equity [Abstract]
LIABILITIES AND STOCKHOLDERS' EQUITY
Cash equivalents and short term investments due term.
Cash Equivalents And Short Term Investments Due Term
Cash equivalents and short term investments due term
Collateralized by a restricted cash deposit
Unrecognized Cash Deposit Collateral
Unrecognized cash deposit collateral.
Accrued Employee Benefits, Current
Accrued compensation and benefits
Property, Plant and Equipment, Policy [Policy Text Block]
Property and Equipment, Net
Antidilutive Securities, Name [Domain]
Antidilutive Securities, Name
Income Tax Authority [Axis]
Income Tax Authority
Total deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total
Silicon valley bank.
Silicon Valley Bank [Member]
Silicon Valley Bank
Assets, Current [Abstract]
Current assets:
Dividends, Common Stock
Common stock dividends declared
Dividends, Common Stock, Total
Class of Warrant or Right, Exercise Price of Warrants or Rights
Warrants exercise price
Comprehensive Loss
Comprehensive Loss PolicyTextBlock
Comprehensive loss
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Schedule of Significant Components of Net Deferred Tax Assets and Liabilities
Gross unrealized losses, less than twelve months
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Deferred Tax Liabilities, Other
Other
Other
Fair Value Hierarchy and NAV [Domain]
Summary of investments in an unrealized loss position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Supplemental Cash Flow Elements [Abstract]
Supplemental cash flow data:
Expected lease term
Lessor, Operating Lease, Renewal Term
Measurement Frequency [Domain]
Measurement Frequency
Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD.
Collaboration and License Agreement, Kaken Pharmaceutical Co. LTD. [Member]
Collaboration and license agreement with Kaken Pharmaceutical Co. LTD.
Increase (Decrease) in Operating Capital [Abstract]
Changes in operating assets and liabilities:
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Granted
Shares, Granted
RSUs granted
Entity
Entity [Domain]
Amount of debt available under the second tranche
Debt Available Second Tranche
Amount of debt available under the second tranche.
Cover [Abstract]
Organization and principal activities.
Organization And Principal Activities [Line Items]
Organization And Principal Activities [Line Items]
2027
Lessee, Operating Lease, Liability, to be Paid, Year Five
Payment of deferred offering costs
Payments of Deferred Offering Costs
Payment of deferred offering costs
Payments of deferred offering costs.
Liabilities, Current [Abstract]
Current liabilities:
Maximum [Member]
Maximum
Unrealized loss on available for sale securities
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Retirement Plan Name [Axis]
Retirement Plan Name
Summary of Stock-Based Compensation Expense Related to Stock Options, RSUs and ESPP
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Forfeitures
Shares, Forfeited
Net cash provided by (used in) investing activities
Net Cash Provided by (Used in) Investing Activities
Furniture and Fixtures [Member]
Furniture and Fixtures
Gain on termination of lease
Gain on lease termination
Gain (Loss) on Termination of Lease
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period
Exercise of common stock options, Shares
Number of options exercised
Exercised, Outstanding Stock Options
General Business Tax Credit Carryforward
General Business Tax Credit Carryforward [Member]
Fair Value, Inputs, Level 3 [Member]
Level 3
Use of Estimates, Policy [Policy Text Block]
Use of Estimates
Deferred Tax Liabilities, Gross
Total deferred tax liabilities
Total deferred tax liabilities
Total deferred tax liabilities
Stock Issued During Period, Value, Stock Options Exercised
Exercise of common stock options
Segment Reporting, Policy [Policy Text Block]
Segment Reporting
Private placement description
Private Placement Description
Private placement description.
Securities Purchase Agreement
Securities Purchase Agreement [Member]
Securities Purchase Agreement [Member]
Long-term Investments, Total
Long-Term Investments
Long-term investments
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value
Vested and exercisable, Aggregate Intrinsic Value
Property, Plant and Equipment, Useful Life
Property and equipment, useful Lives
Employee stock purchase plan offering period.
Employee Stock Purchase Plan Offering Period
Employee stock purchase plan offering period
Effective Income Tax Rate Reconciliation, Tax Credit, Percent
Tax credits
Effective Income Tax Rate Reconciliation, Tax Credit, Percent, Total
Term loan, gross
Term loan, gross
Term loan, gross
Long-Term Debt, Gross
Common Stock, Shares Authorized
Common stock, shares authorized
Common stock shares authorized
All other options.
All Other Options [Member]
All Other Options
Trading Symbol
Trading Symbol
Subsequent Event Type [Axis]
Subsequent Event Type
Deferred Tax Assets, Other
Other
Operating Lease, Right-of-Use Asset, Amortization Expense
Non-cash lease expense
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Total comprehensive loss
End of term payment, amount.
End Of Term Payment Amount
End of term payment, amount
Four zero one k plan.
Four Zero One K Plan [Member]
401(K) Plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
Risk-free interest rate
Accounts Payable, Current
Accounts payable
Accounts Payable, Current, Total
Gross Unrealized Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Increase (Decrease) in Other Operating Assets
Other assets
Increase (Decrease) in Other Operating Assets, Total
Plan Name [Axis]
Plan Name
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Denominator:
Long-Lived Tangible Asset [Domain]
Common Stock, Par or Stated Value Per Share
Common stock, par value
Common stock par value
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Percentage of exercise price of incentive stock options granted owns stock.
Percentage Of Exercise Price Of Incentive Stock Options Granted Owns Stock
Percentage of Exercise price of incentive stock options granted owns stock
Share-Based Payment Arrangement, Restricted Stock and Restricted Stock Unit, Activity [Table Text Block]
Summary of RSU Activity
Defined Benefit Plan Disclosure [Line Items]
Defined Benefit Plan Disclosure [Line Items]
Property, Plant and Equipment, Estimated Useful Lives
Property and equipment, useful Lives
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Granted, Weighted-Average Exercise Price
Options granted to purchase shares of common stock, weighted-average exercise price
Share-Based Compensation Arrangement by Share-Based Payment Award, Non-Option Equity Instruments, Outstanding, Number
Shares, Unvested, Beginning Balance
Shares, Unvested, Ending Balance
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Potential dilutive securities excluded from diluted net loss per share
Cash and cash equivalents fair value disclosure
Cash and cash equivalents, fair value
Cash equivalents, fair value